Info
| ID | 1451 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"S": 1, "O": 2, "N": 1} |
| Abbreviation | complex 1 |
| SMILES | CS(C)=O.Cc1ccc(C(C)C)cc1.O=C([O-])Cc1ccccc1Nc1c(Cl)cccc1Cl.[Cl-] |
TUCAN
C26Cl3NO3RuS/(1-18)(2-18)(3-17)(4-6)(4-21)(5-7)(5-15)(6-10)(7-25)(8-9)(8-17)(9-16)(10-12)(11-19)(11-22)(12-19)(13-14)(13-17)(14-16)(15-26)(16-18)(19-21)(20-25)(20-26)(20-27)(21-27)(22-28)(22-29)(23-31)(24-31)(25-33)(26-34)(30-31)
Measurements (1)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| MCF-7 | 25 | — | 10.1080/07391102.2018.1528180 | 2018 |
🧬 Cell Death Types (1)
Apoptosis
high
«The treatment of MCF-7 with complex 1 revealed that a significant decrease (p < 0.05) in the population of viable cells and increase in the percentage of apoptotic cells was observed.»