Info
| ID | 99 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"O": 1, "N": 2} |
| Abbreviation | 2 |
| SMILES | [Cl-].[O-]/C(=N\N=C/c1c2ccccc2cc2ccccc12)c1ccc(Cl)cc1.c1ccccc1 |
TUCAN
C28H20ClN2ORu/(1-21)(2-22)(3-23)(4-24)(5-27)(6-33)(7-28)(8-32)(9-36)(10-38)(11-30)(12-46)(13-29)(14-35)(15-34)(16-37)(17-25)(18-26)(19-39)(20-31)(21-22)(21-23)(22-24)(23-25)(24-26)(25-26)(27-29)(27-30)(28-29)(28-43)(30-41)(31-33)(31-34)(32-41)(32-42)(33-35)(34-44)(35-42)(36-37)(36-40)(37-48)(38-39)(38-40)(39-48)(40-47)(41-43)(42-44)(43-45)(44-45)(45-46)(46-50)(47-49)(47-51)(48-52)(49-50)(49-53)(50-53)
Measurements (4)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| MDA-MB-231 | 23 | — | 10.1039/c6qi00197a | 2016 |
| HepG2 | 26 | — | 10.1039/c6qi00197a | 2016 |
| HeLa | 27 | — | 10.1039/c6qi00197a | 2016 |
| NIH-3T3 | 2.4e+02 | — | 10.1039/c6qi00197a | 2016 |
🧬 Cell Death Types (1)
Apoptosis
high
«Furthermore, the results of AO–EB, Hoechst 33258 and flow cytometry analyses reveal that these complexes induce cell death only through apoptosis.»