Info
| ID | 98 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"O": 1, "N": 2} |
| Abbreviation | 1 |
| SMILES | [Cl-].[O-]/C(=N\N=C/c1c2ccccc2cc2ccccc12)c1ccccc1.c1ccccc1 |
TUCAN
C28H21N2ORu/(1-22)(2-23)(3-24)(4-25)(5-26)(6-40)(7-30)(8-32)(9-28)(10-33)(11-34)(12-36)(13-38)(14-27)(15-41)(16-29)(17-31)(18-35)(19-39)(20-37)(21-48)(22-23)(22-24)(23-25)(24-26)(25-27)(26-27)(28-38)(28-42)(29-33)(29-34)(30-34)(30-43)(31-35)(31-37)(32-35)(32-46)(33-44)(36-43)(36-46)(37-45)(38-40)(39-40)(39-41)(41-42)(42-49)(43-44)(44-47)(45-46)(45-47)(47-48)(48-51)(49-50)(49-52)(50-51)(50-53)(51-53)
Measurements (4)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| MDA-MB-231 | 19 | — | 10.1039/c6qi00197a | 2016 |
| HepG2 | 21 | — | 10.1039/c6qi00197a | 2016 |
| HeLa | 24 | — | 10.1039/c6qi00197a | 2016 |
| NIH-3T3 | 2.3e+02 | — | 10.1039/c6qi00197a | 2016 |
🧬 Cell Death Types (1)
Apoptosis
high
«Furthermore, the results of AO–EB, Hoechst 33258 and flow cytometry analyses reveal that these complexes induce cell death only through apoptosis.»