Info
| ID | 902 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"P": 1, "N": 1, "O": 1} |
| Abbreviation | 3c |
| SMILES | CC(C)OP(OC(C)C)OC(C)C.O=C1C=CC(=O)[N-]1.[C-]#[O+].c1cc[cH-]c1 |
TUCAN
C19H28NO6PRu/(1-29)(2-29)(3-35)(4-36)(5-37)(6-29)(7-30)(8-38)(9-40)(10-30)(11-30)(12-33)(13-45)(14-33)(15-43)(16-33)(17-34)(18-31)(19-31)(20-39)(21-31)(22-32)(23-41)(24-32)(25-34)(26-32)(27-44)(28-34)(29-43)(30-43)(31-44)(32-44)(33-45)(34-45)(35-36)(35-37)(36-38)(37-39)(38-39)(40-41)(40-46)(41-47)(42-49)(43-52)(44-53)(45-54)(46-48)(46-50)(47-48)(47-51)(48-56)(52-55)(53-55)(54-55)(54-56)(55-56)
Measurements (3)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| PBM | 11 | — | 10.1039/d2dt04083b | 2023 |
| HL60 | 19 | — | 10.1039/d2dt04083b | 2023 |
| HL-60/DR | 1.3e+02 | — | 10.1039/d2dt04083b | 2023 |
🧬 Cell Death Types (1)
Apoptosis
high
«These complexes also induced apoptosis in HL-60 cells.»