Info
| ID | 901 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"N": 1, "O": 1, "P": 1} |
| Abbreviation | 3b |
| SMILES | O=C1C=CC(=O)[N-]1.[C-]#[O+].c1cc[cH-]c1.c1ccc(OP(Oc2ccccc2)Oc2ccccc2)cc1 |
TUCAN
C28H22NO6PRu/(1-34)(2-31)(3-24)(4-36)(5-33)(6-29)(7-40)(8-23)(9-32)(10-35)(11-25)(12-26)(13-38)(14-39)(15-37)(16-30)(17-27)(18-41)(19-42)(20-43)(21-28)(22-44)(23-24)(23-25)(24-26)(25-46)(26-30)(27-28)(27-49)(28-50)(29-31)(29-47)(30-46)(31-34)(32-33)(32-47)(33-34)(35-36)(35-38)(36-37)(37-39)(38-48)(39-48)(40-41)(40-42)(41-43)(42-44)(43-44)(45-53)(46-57)(47-55)(48-56)(49-51)(49-52)(50-51)(50-54)(51-59)(55-58)(56-58)(57-58)(57-59)(58-59)
Measurements (3)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| PBM | 7.2 | — | 10.1039/d2dt04083b | 2023 |
| HL60 | 52 | — | 10.1039/d2dt04083b | 2023 |
| HL-60/DR | 1e+02 | — | 10.1039/d2dt04083b | 2023 |
🧬 Cell Death Types (1)
Apoptosis
high
«These complexes also induced apoptosis in HL-60 cells.»