Info
| ID | 900 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"P": 1, "N": 1, "O": 1} |
| Abbreviation | 3a |
| SMILES | CCOP(OCC)OCC.O=C1C=CC(=O)[N-]1.[C-]#[O+].c1cc[cH-]c1 |
TUCAN
C16H22NO6PRu/(1-23)(2-26)(3-27)(4-28)(5-23)(6-29)(7-31)(8-23)(9-34)(10-34)(11-25)(12-25)(13-25)(14-35)(15-30)(16-35)(17-36)(18-32)(19-36)(20-24)(21-24)(22-24)(23-34)(24-36)(25-35)(26-27)(26-28)(27-29)(28-30)(29-30)(31-32)(31-37)(32-38)(33-40)(34-43)(35-44)(36-45)(37-39)(37-41)(38-39)(38-42)(39-47)(43-46)(44-46)(45-46)(45-47)(46-47)
Measurements (3)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| HL60 | 12 | — | 10.1039/d2dt04083b | 2023 |
| HL-60/DR | — | — | 10.1039/d2dt04083b | 2023 |
| PBM | — | — | 10.1039/d2dt04083b | 2023 |
🧬 Cell Death Types (1)
Apoptosis
high
«These complexes also induced apoptosis in HL-60 cells.»