Info
| ID | 899 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"N": 1, "O": 1, "P": 1} |
| Abbreviation | 2b |
| SMILES | O=C1C=CC(=O)[N-]1.[C-]#[O+].c1cc[cH-]c1.c1coc(P(c2ccco2)c2ccco2)c1 |
TUCAN
C22H16NO6PRu/(1-31)(2-17)(3-33)(4-18)(5-20)(6-25)(7-26)(8-27)(9-28)(10-29)(11-32)(12-23)(13-21)(14-24)(15-22)(16-19)(17-20)(17-31)(18-19)(18-34)(19-35)(20-37)(21-23)(21-36)(22-24)(22-38)(23-33)(24-32)(25-26)(25-27)(26-28)(27-29)(28-29)(30-41)(31-43)(32-44)(33-45)(34-39)(34-40)(35-39)(35-42)(36-45)(36-46)(37-43)(37-46)(38-44)(38-46)(39-47)(45-47)(46-47)
Measurements (3)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| PBM | 8.5 | — | 10.1039/d2dt04083b | 2023 |
| HL60 | 36 | — | 10.1039/d2dt04083b | 2023 |
| HL-60/DR | 1.6e+02 | — | 10.1039/d2dt04083b | 2023 |
🧬 Cell Death Types (1)
Apoptosis
high
«These complexes also induced apoptosis in HL-60 cells.»