Info
| ID | 898 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"N": 1, "O": 1, "P": 1} |
| Abbreviation | 2a |
| SMILES | O=C1C=CC(=O)[N-]1.[C-]#[O+].c1cc[cH-]c1.c1ccc(P(c2ccccc2)c2ccccc2)cc1 |
TUCAN
C28H22NO3PRu/(1-23)(2-24)(3-31)(4-27)(5-32)(6-28)(7-34)(8-33)(9-35)(10-38)(11-36)(12-40)(13-42)(14-37)(15-39)(16-29)(17-25)(18-26)(19-41)(20-30)(21-43)(22-44)(23-24)(23-48)(24-31)(25-26)(25-41)(26-43)(27-28)(27-48)(28-31)(29-30)(29-46)(30-47)(32-34)(32-35)(33-34)(33-49)(35-36)(36-49)(37-38)(37-50)(38-42)(39-40)(39-50)(40-42)(41-44)(43-44)(45-53)(46-51)(46-52)(47-51)(47-54)(48-55)(49-55)(50-55)(51-56)(55-56)
Measurements (3)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| HL60 | 21 | — | 10.1039/d2dt04083b | 2023 |
| HL-60/DR | — | — | 10.1039/d2dt04083b | 2023 |
| PBM | — | — | 10.1039/d2dt04083b | 2023 |
🧬 Cell Death Types (1)
Apoptosis
high
«These complexes also induced apoptosis in HL-60 cells.»
Source-assisted 2D generator
Builds the drawing from source ligand graphs and explicit donor metadata, then uses Metal2D only for layout. Publication output uses black bonds without arrows or colour highlighting; validated octahedral enantiomers are encoded directly with solid and hashed wedge bonds.
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