Info
| ID | 81 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"N": 2, "O": 3, "P": 2} |
| Abbreviation | 4 |
| SMILES | CSC(S)=NN=Cc1ccc([O-])cc1[O-].[C-]#[O+].c1ccc(P(c2ccccc2)c2ccccc2)cc1.c1ccc(P(c2ccccc2)c2ccccc2)cc1 |
TUCAN
C46H38N2O3P2RuS2/(1-39)(2-41)(3-46)(4-40)(5-42)(6-44)(7-43)(8-45)(9-48)(10-49)(11-47)(12-73)(13-70)(14-50)(15-52)(16-53)(17-54)(18-55)(19-56)(20-58)(21-60)(22-59)(23-61)(24-51)(25-83)(26-83)(27-83)(28-62)(29-67)(30-65)(31-63)(32-64)(33-66)(34-71)(35-68)(36-57)(37-69)(38-92)(39-40)(39-46)(40-77)(41-42)(41-46)(42-77)(43-44)(43-78)(44-47)(45-48)(45-78)(47-48)(49-50)(49-51)(50-79)(51-52)(52-53)(53-79)(54-56)(54-80)(55-60)(55-80)(56-62)(57-75)(57-76)(58-61)(58-81)(59-65)(59-81)(60-62)(61-67)(63-66)(63-82)(64-68)(64-82)(65-67)(66-71)(68-71)(69-70)(69-76)(70-72)(72-73)(72-75)(73-85)(74-89)(75-87)(76-88)(77-90)(78-90)(79-90)(80-91)(81-91)(82-91)(83-93)(84-86)(84-92)(84-93)(85-86)(85-94)(86-94)(90-94)(91-94)(92-94)(93-94)
Measurements (8)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| HCT-116 | 22 | — | 10.1016/j.jinorgbio.2021.11154... | 2021 |
| HCT-116 | 24 | — | 10.1016/j.jinorgbio.2021.11154... | 2021 |
| HepG2 | 26 | — | 10.1016/j.jinorgbio.2021.11154... | 2021 |
| HepG2 | 32 | — | 10.1016/j.jinorgbio.2021.11154... | 2021 |
| MCF-7 | 33 | — | 10.1016/j.jinorgbio.2021.11154... | 2021 |
| MCF-7 | 41 | — | 10.1016/j.jinorgbio.2021.11154... | 2021 |
| WI-38 | 82 | — | 10.1016/j.jinorgbio.2021.11154... | 2021 |
| WI-38 | 98 | — | 10.1016/j.jinorgbio.2021.11154... | 2021 |
Source-assisted 2D generator
Builds the drawing from source ligand graphs and explicit donor metadata, then uses Metal2D only for layout. Publication output uses black bonds without arrows or colour highlighting; validated octahedral enantiomers are encoded directly with solid and hashed wedge bonds.
Loading source metadata…
The generated SVG will appear here. The legacy ligand image above stays visible for side-by-side review.