Info
| ID | 805 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 1 |
| Donor atoms | {"N": 5, "S": 1} |
| Abbreviation | 6b |
| SMILES | CC(C)c1ccc2c(c1)CCC1[C@](C)(C(=O)N3CCN(C(=S)[S-])CC3)CCC[C@]21C.Nc1cc2cccnc2c2ncccc12.Nc1cc2cccnc2c2ncccc12 |
TUCAN
C49H53N8ORuS2/(1-92)(2-59)(3-91)(4-75)(5-74)(6-57)(7-60)(8-88)(9-75)(10-87)(11-68)(12-58)(13-62)(14-92)(15-54)(16-54)(17-54)(18-84)(19-72)(20-93)(21-56)(22-56)(23-56)(24-72)(25-73)(26-55)(27-83)(28-55)(29-55)(30-71)(31-61)(32-66)(33-90)(34-57)(35-91)(36-94)(37-63)(38-73)(39-74)(40-57)(41-89)(42-67)(43-69)(44-70)(45-71)(46-94)(47-93)(48-64)(49-65)(50-103)(51-103)(52-104)(53-104)(54-83)(55-83)(56-85)(57-86)(58-68)(58-87)(59-76)(59-95)(60-62)(60-76)(61-70)(61-89)(62-88)(63-64)(63-79)(64-77)(65-77)(65-78)(66-69)(66-82)(67-82)(67-100)(68-80)(69-90)(70-81)(71-74)(71-86)(72-73)(72-84)(73-78)(74-75)(75-85)(76-97)(77-83)(78-79)(79-86)(80-95)(80-96)(81-99)(81-100)(82-98)(84-85)(84-86)(85-101)(87-107)(88-108)(89-109)(90-110)(91-92)(91-105)(92-106)(93-94)(93-106)(94-105)(95-103)(96-97)(96-107)(97-108)(98-99)(98-110)(99-109)(100-104)(101-106)(101-111)(102-105)(102-112)(102-113)(107-114)(108-114)(109-114)(110-114)
Measurements (8)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| MGC-803 | — | — | 10.3390/molecules26051453 | 2021 |
| T24 | — | — | 10.3390/molecules26051453 | 2021 |
| HepG2 | — | — | 10.3390/molecules26051453 | 2021 |
| CNE-2 | — | — | 10.3390/molecules26051453 | 2021 |
| MDA-MB-231 | — | — | 10.3390/molecules26051453 | 2021 |
| MCF-7 | — | — | 10.3390/molecules26051453 | 2021 |
| A549 | — | — | 10.3390/molecules26051453 | 2021 |
| A549cisR | — | — | 10.3390/molecules26051453 | 2021 |
🧬 Cell Death Types (1)
Apoptosis
high
«Acridine orange (AO) staining assay results (Figure 6) showed that the morphology of 6a- and 6c-treated T-24 cells exhibited clear changes and that cell nuclei were stained as yellow/orange, indicatin...»