Info
| ID | 8025 |
| Metal | Au |
| Oxidation state | 1 |
| Charge | 1 |
| Donor atoms | {"N": 4} |
| Abbreviation | — |
| SMILES | CCCC[n+]1[c-]n(C)cc1.CCCC[n+]1[c-]n(C)cc1 |
Measurements (18)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| HCT-116 p53-/- | 0.24 | — | 10.1002/cmdc.201700316 | 2017 |
| IGROV-1 | 0.39 | — | 10.18632/oncotarget.25556 | 2018 |
| SK-OV-3 | 0.55 | — | 10.18632/oncotarget.25556 | 2018 |
| HCT-116 p53+/+ | 0.6 | — | 10.1002/cmdc.201700316 | 2017 |
| NIH-3T3 | 0.7 | — | 10.1002/slct.201700795 | 2017 |
| A375 | 1 | — | 10.1002/cmdc.201700316 | 2017 |
| A2780cisR | 1 | — | 10.1002/anie.202008046 | 2020 |
| MCF-7 | 1.1 | — | 10.1002/cmdc.201700316 | 2017 |
| HCT116-p53wt/OxR | 1.4 | — | 10.1002/anie.202008046 | 2020 |
| MCF-7 | 1.5 | — | 10.1002/anie.202008046 | 2020 |
| A375 | 1.7 | — | 10.1002/anie.202008046 | 2020 |
| HeLa | 1.8 | — | 10.1002/slct.201700795 | 2017 |
| HCT-116 p53-/- | 1.8 | — | 10.1002/anie.202008046 | 2020 |
| A2780 | 2 | — | 10.1002/anie.202008046 | 2020 |
| HCT-116 p53+/+ | 4 | — | 10.1002/anie.202008046 | 2020 |
| NCI-N87 | 5.3 | — | 10.1002/anie.202008046 | 2020 |
| HCT116-p53ko/OxR | 10 | — | 10.1002/anie.202008046 | 2020 |
| MCF-7 | 45 | — | 10.1002/slct.201700795 | 2017 |
Source-assisted 2D generator
Builds the drawing from source ligand graphs and explicit donor metadata, then uses Metal2D only for layout. Publication output uses black bonds without arrows or colour highlighting; validated octahedral enantiomers are encoded directly with solid and hashed wedge bonds.
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The generated SVG will appear here. The legacy ligand image above stays visible for side-by-side review.