Info
| ID | 719 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"S": 2, "O": 2, "N": 2} |
| Abbreviation | [RuCl2(3,3’-dcbpy) (DMSO)2] |
| SMILES | CS(C)=O.CS(C)=O.O=C(O)c1cccnc1-c1ncccc1C(=O)O.[Cl-].[Cl-] |
TUCAN
C16H20N2O6RuS2/(1-27)(2-33)(3-33)(4-33)(5-34)(6-21)(7-22)(8-34)(9-34)(10-35)(11-35)(12-24)(13-23)(14-28)(15-35)(16-36)(17-36)(18-36)(19-43)(20-44)(21-22)(21-25)(22-27)(23-24)(23-28)(24-26)(25-29)(25-31)(26-30)(26-32)(27-37)(28-38)(29-30)(29-37)(30-38)(31-39)(31-43)(32-40)(32-44)(33-45)(34-45)(35-46)(36-46)(37-47)(38-47)(41-45)(42-46)(43-47)(44-47)(45-47)(46-47)
Measurements (2)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| MDA-MB-231 | 6 | — | 10.3897/pharmacia.70.e111508 | 2023 |
| MRC-5 | 5.8e+02 | — | 10.3897/pharmacia.70.e111508 | 2023 |
🧬 Cell Death Types (1)
Apoptosis
high
«RuCl2(3,3’-dcbpy)(DMSO)2] caused apoptosis, which was confirmed by the activation of caspase-3.»