Info
| ID | 7047 |
| Metal | Rh |
| Oxidation state | 3 |
| Charge | 0 |
| Donor atoms | {"O": 3, "N": 2} |
| Abbreviation | 2 |
| SMILES | CO.[Cl-].[O-]c1ccc(Br)c2cccnc12.[O-]c1ccc(Br)c2cccnc12 |
TUCAN
C19H14Br2N2O3Rh/(1-15)(2-18)(3-21)(4-19)(5-25)(6-29)(7-17)(8-22)(9-16)(10-20)(11-26)(12-29)(13-29)(14-38)(15-19)(15-23)(16-20)(16-24)(17-18)(17-30)(18-32)(19-25)(20-26)(21-22)(21-33)(22-31)(23-27)(23-32)(24-28)(24-33)(25-34)(26-35)(27-30)(27-34)(28-31)(28-35)(29-38)(30-36)(31-37)(32-39)(33-40)(34-41)(35-41)(38-41)
Measurements (6)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| T24 | 19 | — | 10.1039/c6nj00182c | 2016 |
| BEL-7404 | 23 | — | 10.1039/c6nj00182c | 2016 |
| HL-7702 | 25 | — | 10.1039/c6nj00182c | 2016 |
| HepG2 | 25 | — | 10.1039/c6nj00182c | 2016 |
| SK-OV-3 | 29 | — | 10.1039/c6nj00182c | 2016 |
| MGC-803 | 42 | — | 10.1039/c6nj00182c | 2016 |
🧬 Cell Death Types (1)
Apoptosis
high
«Complex 1 induced T-24 cell apoptosis in a dose-dependent manner and caused cell cycle arrest in the G2 phase.»