Info
| ID | 7046 |
| Metal | Rh |
| Oxidation state | 3 |
| Charge | 0 |
| Donor atoms | {"O": 3, "N": 3} |
| Abbreviation | 1 |
| SMILES | [O-]c1cccc2cccnc12.[O-]c1cccc2cccnc12.[O-]c1cccc2cccnc12 |
TUCAN
C27H18N3O3Rh/(1-37)(2-22)(3-19)(4-21)(5-20)(6-23)(7-28)(8-26)(9-24)(10-25)(11-27)(12-38)(13-33)(14-29)(15-39)(16-31)(17-32)(18-30)(19-21)(19-23)(20-22)(20-34)(21-34)(22-37)(23-43)(24-25)(24-44)(25-27)(26-28)(26-35)(27-35)(28-38)(29-32)(29-36)(30-33)(30-39)(31-32)(31-45)(33-36)(34-40)(35-41)(36-42)(37-46)(38-47)(39-48)(40-43)(40-46)(41-44)(41-47)(42-45)(42-48)(43-49)(44-50)(45-51)(46-52)(47-52)(48-52)
Measurements (6)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| T24 | 13 | — | 10.1039/c6nj00182c | 2016 |
| BEL-7404 | 25 | — | 10.1039/c6nj00182c | 2016 |
| SK-OV-3 | 27 | — | 10.1039/c6nj00182c | 2016 |
| HL-7702 | 29 | — | 10.1039/c6nj00182c | 2016 |
| MGC-803 | 30 | — | 10.1039/c6nj00182c | 2016 |
| HepG2 | 31 | — | 10.1039/c6nj00182c | 2016 |
🧬 Cell Death Types (1)
Apoptosis
high
«Complex 1 induced T-24 cell apoptosis in a dose-dependent manner and caused cell cycle arrest in the G2 phase.»