Info
| ID | 6996 |
| Metal | Rh |
| Oxidation state | 3 |
| Charge | 0 |
| Donor atoms | {"N": 5} |
| Abbreviation | Rh1 |
| SMILES | CC#N.O=C([N-]c1ccccc1)c1nc(-n2nc(C(F)(F)F)cc2-c2ccccc2)ccc1Cl.[Cl-].[Cl-] |
TUCAN
C24H16ClF3N5ORh/(1-27)(2-23)(3-29)(4-18)(5-21)(6-20)(7-30)(8-28)(9-22)(10-24)(11-25)(12-26)(13-19)(14-17)(15-17)(16-17)(17-32)(18-21)(18-23)(19-22)(19-40)(20-33)(20-34)(21-31)(22-37)(23-25)(24-25)(24-31)(26-27)(26-28)(27-29)(28-30)(29-35)(30-35)(31-33)(32-41)(33-43)(34-39)(34-42)(35-45)(36-38)(36-40)(36-44)(37-43)(37-44)(38-45)(38-46)(39-47)(39-48)(39-49)(40-50)(42-43)(44-51)(45-51)
Measurements (7)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| T24 | 0.8 | — | 10.1021/acs.jmedchem.3c00318 | 2023 |
| A549 | 1.3 | — | 10.1021/acs.jmedchem.3c00318 | 2023 |
| T24 | 1.7 | — | 10.1021/acs.jmedchem.3c00318 | 2023 |
| HeLa | 2.5 | — | 10.1021/acs.jmedchem.3c00318 | 2023 |
| WI-38 | 2.7 | — | 10.1021/acs.jmedchem.3c00318 | 2023 |
| BEL-7404 | 2.8 | — | 10.1021/acs.jmedchem.3c00318 | 2023 |
| SK-OV-3 | 3 | — | 10.1021/acs.jmedchem.3c00318 | 2023 |