Info
| ID | 6958 |
| Metal | Rh |
| Oxidation state | 3 |
| Charge | 0 |
| Donor atoms | {"N": 3, "O": 1} |
| Abbreviation | Rh-1 |
| SMILES | C/C=C/c1cccc2cc(-c3nc4ccccc4[nH]3)c(=N)oc12.CO.[Cl-].[Cl-].[Cl-] |
TUCAN
C20H19N3O2Rh/(1-20)(2-25)(3-20)(4-22)(5-23)(6-21)(7-30)(8-27)(9-37)(10-28)(11-26)(12-20)(13-24)(14-29)(15-37)(16-37)(17-41)(18-40)(19-43)(20-22)(21-22)(21-31)(23-32)(23-33)(24-26)(24-31)(25-26)(25-32)(27-28)(27-35)(28-29)(29-30)(30-34)(31-38)(32-38)(33-36)(33-39)(34-35)(34-42)(35-40)(36-40)(36-42)(37-43)(38-44)(39-41)(39-44)(41-45)(42-45)(43-45)(44-45)
Measurements (3)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A549cisR | 7.1 | — | 10.1016/j.inoche.2020.108017 | 2020 |
| SK-OV-3cisR | 10 | — | 10.1016/j.inoche.2020.108017 | 2020 |
| HL-7702 | 81 | — | 10.1016/j.inoche.2020.108017 | 2020 |
🧬 Cell Death Types (1)
Apoptosis
high
«This suggested that cell death was induced by Rh-2 (3.21μM) and Rh-3 (0.50μM) via a high incidence of apoptosis. ... These results suggested that Rh-2 (3.21μM) and Rh-3 (0.50μM) could induce apoptosis...»