Info
| ID | 6956 |
| Metal | Rh |
| Oxidation state | 3 |
| Charge | 0 |
| Donor atoms | {"O": 1, "N": 3} |
| Abbreviation | Rh-3 |
| SMILES | CO.N=c1oc2c(F)cccc2cc1-c1nc2ccccc2[nH]1.[Cl-].[Cl-].[Cl-] |
TUCAN
C17H14FN3O2Rh/(1-19)(2-16)(3-15)(4-21)(5-22)(6-20)(7-18)(8-17)(9-28)(10-28)(11-28)(12-33)(13-32)(14-35)(15-20)(15-22)(16-18)(16-26)(17-23)(17-24)(18-19)(19-21)(20-24)(21-25)(22-31)(23-27)(23-30)(24-29)(25-26)(25-32)(26-34)(27-32)(27-34)(28-35)(29-31)(29-36)(30-33)(30-36)(31-37)(33-38)(34-38)(35-38)(36-38)
Measurements (3)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A549cisR | 0.5 | — | 10.1016/j.inoche.2020.108017 | 2020 |
| SK-OV-3cisR | 1 | — | 10.1016/j.inoche.2020.108017 | 2020 |
| HL-7702 | 92 | — | 10.1016/j.inoche.2020.108017 | 2020 |
🧬 Cell Death Types (1)
Apoptosis
high
«This suggested that cell death was induced by Rh-2 (3.21μM) and Rh-3 (0.50μM) via a high incidence of apoptosis. ... These results suggested that Rh-2 (3.21μM) and Rh-3 (0.50μM) could induce apoptosis...»