Info
| ID | 6942 |
| Metal | Rh |
| Oxidation state | 1 |
| Charge | 0 |
| Donor atoms | {"N": 1} |
| Abbreviation | 8e |
| SMILES | C1=CCCC=CCC1.CCn1[c-][n+](Cc2cccc3ccccc23)c(-c2ccc(F)cc2)c1-c1ccc(F)cc1.[Cl-] |
TUCAN
C36ClF2N2Rh/(1-30)(2-3)(2-4)(3-5)(4-6)(5-7)(6-8)(7-9)(8-9)(10-14)(10-36)(11-12)(11-25)(12-35)(13-16)(13-27)(14-29)(15-24)(15-36)(16-21)(17-20)(17-28)(18-19)(18-35)(19-25)(20-23)(21-22)(22-28)(23-26)(24-29)(25-33)(26-27)(26-31)(27-28)(29-32)(30-37)(31-38)(32-33)(32-37)(33-38)(34-37)(34-38)(35-39)(36-40)
Measurements (3)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| MCF-7 | 3.7 | — | 10.1016/j.ejmech.2019.111721 | 2019 |
| HepG2 | 3.9 | — | 10.1016/j.ejmech.2019.111721 | 2019 |
| HT-29 | 7.4 | — | 10.1016/j.ejmech.2019.111721 | 2019 |
🧬 Cell Death Types (1)
Apoptosis
high
«These results suggested that 1e induced apoptosis of HepG2 cells along with caspase activation.»