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Complex #6941 — Rh(1) [7e]

2D Structure

Structure
⬇ MOL V3000

Info

ID6941
MetalRh
Oxidation state1
Charge0
Donor atoms{"N": 1}
Abbreviation7e
SMILESC1=CCCC=CCC1.CCn1[c-][n+](Cc2ccccc2)c(-c2ccc(F)cc2)c1-c1ccc(F)cc1.[Cl-]

TUCAN

C32ClF2N2Rh/(1-26)(2-3)(2-4)(3-5)(4-6)(5-7)(6-8)(7-9)(8-9)(10-14)(10-32)(11-12)(11-23)(12-31)(13-16)(13-21)(14-25)(15-22)(15-32)(16-24)(17-20)(17-24)(18-19)(18-31)(19-23)(20-21)(22-25)(23-29)(24-27)(25-28)(26-34)(27-33)(28-29)(28-34)(29-33)(30-33)(30-34)(31-35)(32-36)

Measurements (3)

Cell lineIC₅₀ dark (µM)IC₅₀ light (µM)DOIYear
HepG24.5 10.1016/j.ejmech.2019.111721 2019
MCF-75.5 10.1016/j.ejmech.2019.111721 2019
HT-296.5 10.1016/j.ejmech.2019.111721 2019

🧬 Cell Death Types (1)

Apoptosis high
«These results suggested that 1e induced apoptosis of HepG2 cells along with caspase activation.»