Info
| ID | 6939 |
| Metal | Rh |
| Oxidation state | 1 |
| Charge | 0 |
| Donor atoms | {"N": 1} |
| Abbreviation | 5e |
| SMILES | C1=CCCC=CCC1.CCn1[c-][n+](Cc2c3ccccc3cc3ccccc23)c(-c2ccc(F)cc2)c1-c1ccc(F)cc1.[Cl-] |
TUCAN
C40ClF2N2Rh/(1-34)(2-3)(2-4)(3-5)(4-6)(5-7)(6-8)(7-9)(8-9)(10-17)(10-40)(11-12)(11-28)(12-16)(13-14)(13-27)(14-39)(15-16)(15-29)(17-33)(18-26)(18-40)(19-20)(19-32)(20-23)(21-22)(21-39)(22-27)(23-25)(24-29)(24-32)(25-31)(26-33)(27-37)(28-29)(28-30)(30-31)(30-35)(31-32)(33-36)(34-42)(35-41)(36-37)(36-42)(37-41)(38-41)(38-42)(39-43)(40-44)
Measurements (3)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| HepG2 | 6 | — | 10.1016/j.ejmech.2019.111721 | 2019 |
| HT-29 | 13 | — | 10.1016/j.ejmech.2019.111721 | 2019 |
| MCF-7 | 18 | — | 10.1016/j.ejmech.2019.111721 | 2019 |
🧬 Cell Death Types (1)
Apoptosis
high
«These results suggested that 1e induced apoptosis of HepG2 cells along with caspase activation.»