Info
| ID | 6938 |
| Metal | Rh |
| Oxidation state | 1 |
| Charge | 0 |
| Donor atoms | {"N": 1} |
| Abbreviation | 4e |
| SMILES | C1=CCCC=CCC1.CCn1[c-][n+](CC)c(-c2ccc(-c3ccccc3)cc2)c1-c1ccc(-c2ccccc2)cc1.[Cl-] |
TUCAN
C39ClN2Rh/(1-35)(2-36)(3-4)(3-5)(4-6)(5-7)(6-8)(7-9)(8-10)(9-10)(11-13)(11-29)(12-18)(12-30)(13-22)(14-15)(14-29)(15-22)(16-21)(16-23)(17-23)(17-27)(18-32)(19-20)(19-30)(20-32)(21-31)(24-26)(24-34)(25-28)(25-34)(26-33)(27-31)(28-33)(29-30)(31-34)(32-37)(33-38)(35-40)(36-41)(37-38)(37-40)(38-41)(39-40)(39-41)
Measurements (3)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| HT-29 | 5.2 | — | 10.1016/j.ejmech.2019.111721 | 2019 |
| MCF-7 | 7.7 | — | 10.1016/j.ejmech.2019.111721 | 2019 |
| HepG2 | 8.9 | — | 10.1016/j.ejmech.2019.111721 | 2019 |
🧬 Cell Death Types (1)
Apoptosis
high
«These results suggested that 1e induced apoptosis of HepG2 cells along with caspase activation.»