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Complex #6937 — Rh(1) [3e]

2D Structure

Structure
⬇ MOL V3000

Info

ID6937
MetalRh
Oxidation state1
Charge0
Donor atoms{"N": 1}
Abbreviation3e
SMILESC1=CCCC=CCC1.CCn1[c-][n+](CC)c(-c2ccc(Br)cc2)c1-c1ccc(Br)cc1.[Cl-]

TUCAN

C27Br2ClN2Rh/(1-21)(2-22)(3-4)(3-5)(4-6)(5-7)(6-8)(7-9)(8-11)(9-11)(10-12)(10-26)(12-19)(13-14)(13-26)(14-19)(15-16)(15-20)(16-27)(17-18)(17-20)(18-27)(19-23)(20-24)(21-28)(22-29)(23-24)(23-28)(24-29)(25-28)(25-29)(26-31)(27-32)

Measurements (3)

Cell lineIC₅₀ dark (µM)IC₅₀ light (µM)DOIYear
MCF-74.1 10.1016/j.ejmech.2019.111721 2019
HepG25 10.1016/j.ejmech.2019.111721 2019
HT-296.8 10.1016/j.ejmech.2019.111721 2019

🧬 Cell Death Types (1)

Apoptosis high
«These results suggested that 1e induced apoptosis of HepG2 cells along with caspase activation.»