Info
| ID | 6935 |
| Metal | Rh |
| Oxidation state | 1 |
| Charge | 0 |
| Donor atoms | {"N": 1} |
| Abbreviation | 1e |
| SMILES | C1=CCCC=CCC1.CCn1[c-][n+](CC)c(-c2ccc(F)cc2)c1-c1ccc(F)cc1.[Cl-] |
TUCAN
C27ClF2N2Rh/(1-21)(2-22)(3-4)(3-5)(4-6)(5-7)(6-8)(7-9)(8-11)(9-11)(10-12)(10-26)(12-19)(13-14)(13-26)(14-19)(15-17)(15-27)(16-18)(16-27)(17-20)(18-20)(19-23)(20-24)(21-28)(22-29)(23-24)(23-28)(24-29)(25-28)(25-29)(26-30)(27-31)
Measurements (3)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| HepG2 | 1.3 | — | 10.1016/j.ejmech.2019.111721 | 2019 |
| MCF-7 | 4.5 | — | 10.1016/j.ejmech.2019.111721 | 2019 |
| HT-29 | 6.5 | — | 10.1016/j.ejmech.2019.111721 | 2019 |
🧬 Cell Death Types (1)
Apoptosis
high
«These results suggested that 1e induced apoptosis of HepG2 cells along with caspase activation.»