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Complex #6882 — Rh(3) [tpatpy-Rh]

2D Structure

Structure
⬇ MOL V3000

Info

ID6882
MetalRh
Oxidation state3
Charge0
Donor atoms{"N": 3}
Abbreviationtpatpy-Rh
SMILES[Cl-].[Cl-].[Cl-].c1ccc(-c2cc(-c3cccs3)cc(-c3ccccn3)n2)nc1

TUCAN

C19H13N3RhS/(1-22)(2-19)(3-18)(4-14)(5-21)(6-25)(7-31)(8-20)(9-17)(10-15)(11-26)(12-16)(13-23)(14-16)(14-28)(15-16)(15-26)(17-23)(17-30)(18-23)(18-25)(19-20)(19-31)(20-32)(21-24)(21-27)(22-24)(22-29)(24-32)(25-33)(26-34)(27-28)(27-35)(28-34)(29-30)(29-35)(30-33)(31-36)(32-36)(34-37)(35-37)(36-37)

Measurements (5)

Cell lineIC₅₀ dark (µM)IC₅₀ light (µM)DOIYear
SK-OV-3cisR5 10.1016/j.inoche.2019.02.030 2019
T2415 10.1016/j.inoche.2019.02.030 2019
SK-OV-330 10.1016/j.inoche.2019.02.030 2019
HL-770240 10.1016/j.inoche.2019.02.030 2019
HeLa 10.1016/j.inoche.2019.02.030 2019

🧬 Cell Death Types (1)

Apoptosis high
«which suggested that tpatpy-Rh (5.03 μM) could cause apoptosis.»