Info
| ID | 6840 |
| Metal | Rh |
| Oxidation state | 3 |
| Charge | 1 |
| Donor atoms | {"N": 2} |
| Abbreviation | 5a |
| SMILES | Cc1c(C)c(C)[c-](C)c1C.Cc1ccc(NCc2ccccn2)cc1.[Cl-] |
TUCAN
C23ClN2Rh/(1-14)(2-15)(3-16)(4-17)(5-18)(6-19)(7-8)(7-23)(8-17)(9-10)(9-21)(10-11)(11-22)(12-13)(12-23)(13-17)(14-15)(14-16)(15-18)(16-19)(18-19)(20-22)(20-24)(21-25)(22-25)(23-24)
Measurements (3)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| HeLa | 16 | — | 10.1021/acs.inorgchem.2c00984 | 2022 |
| BEAS-2B | 26 | — | 10.1021/acs.inorgchem.2c00984 | 2022 |
| A549 | 40 | — | 10.1021/acs.inorgchem.2c00984 | 2022 |
🧬 Cell Death Types (1)
Apoptosis
high
«the represented complex 5a can promote an increase in the reactive oxygen species level and induce cell death via apoptosis»