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Complex #6839 — Rh(3) [3c]

2D Structure

Structure
⬇ MOL V3000

Info

ID6839
MetalRh
Oxidation state3
Charge1
Donor atoms{"N": 2}
Abbreviation3c
SMILESCC(C)c1cccc(C(C)C)c1/N=C/c1ccccn1.Cc1c(C)c(C)[c-](C)c1C.[Cl-]

TUCAN

C28H37N2Rh/(1-38)(2-38)(3-38)(4-39)(5-39)(6-39)(7-40)(8-40)(9-40)(10-41)(11-43)(12-43)(13-43)(14-44)(15-60)(16-44)(17-44)(18-61)(19-51)(20-52)(21-45)(22-45)(23-45)(24-46)(25-50)(26-46)(27-46)(28-62)(29-41)(30-41)(31-49)(32-42)(33-47)(34-42)(35-48)(36-42)(37-63)(38-53)(39-54)(40-55)(41-56)(42-57)(43-60)(44-60)(45-61)(46-61)(47-48)(47-62)(48-49)(49-64)(50-51)(50-52)(51-58)(52-59)(53-54)(53-55)(54-56)(55-57)(56-57)(58-60)(58-65)(59-61)(59-65)(62-66)(63-64)(63-67)(64-66)(65-67)(66-68)(67-68)

Measurements (3)

Cell lineIC₅₀ dark (µM)IC₅₀ light (µM)DOIYear
A54930 10.1021/acs.inorgchem.2c00984 2022
HeLa39 10.1021/acs.inorgchem.2c00984 2022
BEAS-2B47 10.1021/acs.inorgchem.2c00984 2022

🧬 Cell Death Types (1)

Apoptosis high
«the represented complex 5a can promote an increase in the reactive oxygen species level and induce cell death via apoptosis»