Info
| ID | 6838 |
| Metal | Rh |
| Oxidation state | 3 |
| Charge | 1 |
| Donor atoms | {"N": 2} |
| Abbreviation | 3b |
| SMILES | C/C(=N\c1c(C(C)C)cccc1C(C)C)c1ccccn1.Cc1c(C)c(C)[c-](C)c1C.[Cl-] |
TUCAN
C29H39N2Rh/(1-40)(2-40)(3-40)(4-41)(5-41)(6-41)(7-42)(8-65)(9-42)(10-42)(11-43)(12-45)(13-45)(14-45)(15-46)(16-46)(17-46)(18-63)(19-47)(20-47)(21-47)(22-53)(23-48)(24-54)(25-48)(26-48)(27-55)(28-64)(29-49)(30-50)(31-43)(32-43)(33-49)(34-44)(35-51)(36-44)(37-52)(38-44)(39-49)(40-56)(41-57)(42-58)(43-59)(44-60)(45-63)(46-63)(47-68)(48-64)(49-64)(50-51)(50-65)(51-52)(52-66)(53-54)(53-61)(54-55)(55-62)(56-57)(56-58)(57-59)(58-60)(59-60)(61-63)(61-67)(62-64)(62-67)(65-69)(66-68)(66-69)(67-70)(68-70)(69-71)(70-71)
Measurements (3)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| HeLa | 29 | — | 10.1021/acs.inorgchem.2c00984 | 2022 |
| A549 | 37 | — | 10.1021/acs.inorgchem.2c00984 | 2022 |
| BEAS-2B | 38 | — | 10.1021/acs.inorgchem.2c00984 | 2022 |
🧬 Cell Death Types (1)
Apoptosis
high
«the represented complex 5a can promote an increase in the reactive oxygen species level and induce cell death via apoptosis»