Info
| ID | 6819 |
| Metal | Rh |
| Oxidation state | 3 |
| Charge | 0 |
| Donor atoms | {"O": 1, "N": 3} |
| Abbreviation | 12 |
| SMILES | CCO.Cc1ccc2[nH]c(=O)c(-c3nc4cc(Cl)c(Cl)cc4[nH]3)cc2c1.[Cl-].[Cl-].[Cl-] |
TUCAN
C19H17Cl2N3O2Rh/(1-19)(2-18)(3-18)(4-18)(5-19)(6-24)(7-23)(8-25)(9-21)(10-19)(11-22)(12-20)(13-33)(14-33)(15-37)(16-38)(17-41)(18-33)(19-28)(20-25)(20-29)(21-27)(21-28)(22-26)(22-27)(23-31)(23-35)(24-30)(24-36)(25-28)(26-32)(26-34)(27-29)(29-38)(30-31)(30-37)(31-39)(32-37)(32-39)(33-41)(34-38)(34-40)(35-36)(35-43)(36-42)(39-44)(41-44)
Measurements (5)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| HeLa229 | 7.3 | — | 10.1016/j.ejmech.2018.03.074 | 2018 |
| HepG2 | 9.6 | — | 10.1016/j.ejmech.2018.03.074 | 2018 |
| NCI-H460 | 10 | — | 10.1016/j.ejmech.2018.03.074 | 2018 |
| MGC-803 | 11 | — | 10.1016/j.ejmech.2018.03.074 | 2018 |
| HL-7702 | 12 | — | 10.1016/j.ejmech.2018.03.074 | 2018 |
🧬 Cell Death Types (1)
Apoptosis
high
«complex 9 caused cell cycle arrest at the G2/M phase and induced apoptosis (abstract). Also: 'Therefore, complex 9 is a potent apoptosis inducer' (section 2.9) and 'Hence, complex 9 induced cell apopt...»