Info
| ID | 6816 |
| Metal | Rh |
| Oxidation state | 3 |
| Charge | 0 |
| Donor atoms | {"O": 1, "N": 3} |
| Abbreviation | 9 |
| SMILES | CCO.Cc1ccc2[nH]c(=O)c(-c3nc4ccccc4[nH]3)cc2c1.[Cl-].[Cl-].[Cl-] |
TUCAN
C19H19N3O2Rh/(1-25)(2-22)(3-20)(4-20)(5-20)(6-21)(7-27)(8-24)(9-26)(10-21)(11-29)(12-28)(13-23)(14-21)(15-37)(16-37)(17-39)(18-40)(19-43)(20-37)(21-32)(22-30)(22-32)(23-24)(23-27)(24-25)(25-33)(26-30)(26-31)(27-34)(28-29)(28-32)(29-35)(30-35)(31-36)(31-38)(33-34)(33-41)(34-40)(35-39)(36-40)(36-41)(37-43)(38-39)(38-42)(41-44)(43-44)
Measurements (5)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| HepG2 | 6.1 | — | 10.1016/j.ejmech.2018.03.074 | 2018 |
| NCI-H460 | 6.3 | — | 10.1016/j.ejmech.2018.03.074 | 2018 |
| HeLa229 | 8.4 | — | 10.1016/j.ejmech.2018.03.074 | 2018 |
| MGC-803 | 10 | — | 10.1016/j.ejmech.2018.03.074 | 2018 |
| HL-7702 | 22 | — | 10.1016/j.ejmech.2018.03.074 | 2018 |
🧬 Cell Death Types (1)
Apoptosis
high
«complex 9 caused cell cycle arrest at the G2/M phase and induced apoptosis (abstract). Also: 'Therefore, complex 9 is a potent apoptosis inducer' (section 2.9) and 'Hence, complex 9 induced cell apopt...»