Info
| ID | 677 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 1 |
| Donor atoms | {"N": 2} |
| Abbreviation | 4c |
| SMILES | CCCCN1C(=O)/C(=N/c2c(C)cc(C)cc2C)c2ccccc21.Cc1ccc(C(C)C)cc1.[Cl-] |
TUCAN
C31ClN2ORu/(1-22)(2-22)(3-23)(4-21)(5-20)(6-13)(7-26)(8-10)(8-24)(9-19)(9-24)(10-21)(11-20)(11-23)(12-17)(12-25)(13-18)(14-16)(14-28)(15-23)(15-26)(16-17)(18-27)(19-21)(20-30)(22-24)(25-28)(25-29)(26-30)(27-33)(28-33)(29-31)(29-32)(30-32)(31-33)(31-34)
Measurements (4)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| HepG2 | 42 | — | 10.1021/acsomega.3c10265 | 2024 |
| PC-3 | 46 | — | 10.1021/acsomega.3c10265 | 2024 |
| MCF-7 | 47 | — | 10.1021/acsomega.3c10265 | 2024 |
| HEK293 | 51 | — | 10.1021/acsomega.3c10265 | 2024 |
🧬 Cell Death Types (1)
Apoptosis
high
«Treatment of the cells with 4d induced a strong apoptotic effect on them (see Figure 3). Levels of the apoptosis-related proteins Bcl-2 and Bax were evaluated via Western blot analysis to confirm the ...»