Info
| ID | 676 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 1 |
| Donor atoms | {"N": 2} |
| Abbreviation | 4b |
| SMILES | CCCCN1C(=O)/C(=N/c2ccccc2)c2ccccc21.Cc1ccc(C(C)C)cc1.[Cl-] |
TUCAN
C28ClN2ORu/(1-21)(2-21)(3-20)(4-17)(5-10)(5-27)(6-8)(6-23)(7-19)(7-23)(8-20)(9-11)(9-22)(10-14)(11-12)(12-15)(13-18)(13-27)(14-18)(15-26)(16-17)(16-24)(19-20)(21-23)(22-25)(22-26)(24-30)(25-28)(25-29)(26-30)(27-29)(28-30)(28-31)
Measurements (4)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| MCF-7 | 47 | — | 10.1021/acsomega.3c10265 | 2024 |
| HEK293 | 53 | — | 10.1021/acsomega.3c10265 | 2024 |
| PC-3 | 55 | — | 10.1021/acsomega.3c10265 | 2024 |
| HepG2 | 61 | — | 10.1021/acsomega.3c10265 | 2024 |
🧬 Cell Death Types (1)
Apoptosis
high
«Treatment of the cells with 4d induced a strong apoptotic effect on them (see Figure 3). Levels of the apoptosis-related proteins Bcl-2 and Bax were evaluated via Western blot analysis to confirm the ...»