Info
| ID | 675 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 1 |
| Donor atoms | {"N": 2} |
| Abbreviation | 4a |
| SMILES | Cc1ccc(C(C)C)cc1.O=C1Nc2ccccc2/C1=N\c1ccccc1.[Cl-] |
TUCAN
C24ClN2ORu/(1-17)(2-19)(3-19)(4-7)(4-12)(5-8)(5-20)(6-7)(6-18)(8-17)(9-10)(9-11)(10-21)(11-14)(12-23)(13-15)(13-20)(14-16)(15-17)(16-21)(18-22)(18-23)(19-20)(21-25)(22-24)(22-25)(23-26)(24-26)(24-27)
Measurements (4)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| MCF-7 | 1e+02 | — | 10.1021/acsomega.3c10265 | 2024 |
| HEK293 | 1.3e+02 | — | 10.1021/acsomega.3c10265 | 2024 |
| PC-3 | 2.3e+02 | — | 10.1021/acsomega.3c10265 | 2024 |
| HepG2 | 5.5e+02 | — | 10.1021/acsomega.3c10265 | 2024 |
🧬 Cell Death Types (1)
Apoptosis
high
«Treatment of the cells with 4d induced a strong apoptotic effect on them (see Figure 3). Levels of the apoptosis-related proteins Bcl-2 and Bax were evaluated via Western blot analysis to confirm the ...»