Info
| ID | 6722 |
| Metal | Rh |
| Oxidation state | 3 |
| Charge | 0 |
| Donor atoms | {"O": 1, "N": 1, "P": 1, "F": 4} |
| Abbreviation | Rh3 |
| SMILES | CC(C)c1cc(S(=O)(=O)[O-])cc(C(C)C)c1N=Cc1ccccc1P(c1ccccc1)c1ccccc1.Cc1c(C)c(-c2cc(C(F)(F)F)cc(C(F)(F)F)c2)[c-](C)c1C.[Cl-] |
TUCAN
C48H46F6NO3PRhS/(1-87)(2-50)(3-48)(4-48)(5-56)(6-47)(7-47)(8-50)(9-50)(10-47)(11-61)(12-58)(13-64)(14-48)(15-49)(16-49)(17-65)(18-59)(19-66)(20-62)(21-63)(22-60)(23-57)(24-72)(25-69)(26-51)(27-51)(28-51)(29-70)(30-85)(31-53)(32-53)(33-53)(34-54)(35-54)(36-73)(37-49)(38-52)(39-52)(40-71)(41-52)(42-68)(43-55)(44-67)(45-54)(46-86)(47-75)(48-77)(49-81)(50-85)(51-85)(52-76)(53-86)(54-86)(55-79)(55-82)(56-79)(56-80)(57-58)(57-91)(58-59)(59-60)(60-78)(61-64)(61-92)(62-66)(62-92)(63-72)(63-93)(64-65)(65-66)(67-73)(67-93)(68-80)(68-82)(69-83)(69-94)(70-84)(70-94)(71-72)(71-73)(74-75)(74-76)(74-80)(75-77)(76-81)(77-81)(78-87)(78-91)(79-89)(82-90)(83-85)(83-88)(84-86)(84-88)(87-95)(88-95)(89-99)(89-100)(89-101)(90-102)(90-103)(90-104)(91-105)(92-105)(93-105)(94-106)(95-107)(96-106)(97-106)(98-106)(105-107)(106-107)
Measurements (3)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| HeLa | 12 | — | 10.1021/acs.inorgchem.2c03279 | 2022 |
| A549 | 23 | — | 10.1021/acs.inorgchem.2c03279 | 2022 |
| BEAS-2B | 36 | — | 10.1021/acs.inorgchem.2c03279 | 2022 |
🧬 Cell Death Types (1)
Apoptosis
high
«The flow cytometry studies indicated that the representative complex Ir1 could induce early-stage apoptosis in A549 cells.»