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Complex #6721 — Rh(3) [Rh2]

2D Structure

Structure
⬇ MOL V3000

Info

ID6721
MetalRh
Oxidation state3
Charge0
Donor atoms{"O": 1, "N": 1, "P": 1}
AbbreviationRh2
SMILESCC(C)c1cc(S(=O)(=O)[O-])cc(C(C)C)c1N=Cc1ccccc1P(c1ccccc1)c1ccccc1.Cc1c(C)c(C2CCCCC2)[c-](C)c1C.[Cl-]

TUCAN

C46H54NO3PRhS/(1-71)(2-79)(3-73)(4-92)(5-82)(6-55)(7-55)(8-56)(9-56)(10-56)(11-82)(12-72)(13-67)(14-80)(15-60)(16-80)(17-83)(18-75)(19-83)(20-55)(21-79)(22-68)(23-69)(24-81)(25-76)(26-70)(27-74)(28-57)(29-57)(30-57)(31-58)(32-95)(33-58)(34-65)(35-59)(36-60)(37-63)(38-60)(39-81)(40-59)(41-64)(42-59)(43-66)(44-58)(45-61)(46-61)(47-77)(48-78)(49-61)(50-93)(51-62)(52-62)(53-62)(54-94)(55-85)(56-84)(57-93)(58-93)(59-89)(60-88)(61-94)(62-94)(63-64)(63-97)(64-65)(65-66)(66-87)(67-71)(67-98)(68-72)(68-98)(69-75)(69-99)(70-76)(70-99)(71-73)(72-73)(74-75)(74-76)(77-90)(77-100)(78-91)(78-100)(79-80)(79-82)(80-81)(81-83)(82-92)(83-92)(84-85)(84-86)(85-89)(86-88)(86-92)(87-95)(87-97)(88-89)(90-93)(90-96)(91-94)(91-96)(95-101)(96-101)(97-105)(98-105)(99-105)(100-106)(101-107)(102-106)(103-106)(104-106)(105-107)(106-107)

Measurements (3)

Cell lineIC₅₀ dark (µM)IC₅₀ light (µM)DOIYear
HeLa9.5 10.1021/acs.inorgchem.2c03279 2022
A54923 10.1021/acs.inorgchem.2c03279 2022
BEAS-2B35 10.1021/acs.inorgchem.2c03279 2022

🧬 Cell Death Types (1)

Apoptosis high
«The flow cytometry studies indicated that the representative complex Ir1 could induce early-stage apoptosis in A549 cells.»