Info
| ID | 6720 |
| Metal | Rh |
| Oxidation state | 3 |
| Charge | 0 |
| Donor atoms | {"O": 1, "N": 1, "P": 1} |
| Abbreviation | Rh1 |
| SMILES | CC(C)c1cc(S(=O)(=O)[O-])cc(C(C)C)c1N=Cc1ccccc1P(c1ccccc1)c1ccccc1.Cc1c(C)c(C)[c-](C)c1C.[Cl-] |
TUCAN
C41H46NO3PRhS/(1-60)(2-47)(3-82)(4-47)(5-47)(6-48)(7-48)(8-48)(9-49)(10-52)(11-52)(12-49)(13-49)(14-50)(15-50)(16-56)(17-57)(18-66)(19-50)(20-51)(21-51)(22-68)(23-61)(24-58)(25-63)(26-62)(27-51)(28-65)(29-64)(30-59)(31-69)(32-67)(33-70)(34-52)(35-53)(36-53)(37-71)(38-80)(39-53)(40-54)(41-54)(42-54)(43-55)(44-55)(45-55)(46-81)(47-72)(48-73)(49-74)(50-76)(51-77)(52-80)(53-80)(54-81)(55-81)(56-61)(56-84)(57-58)(57-85)(58-59)(59-60)(60-75)(61-63)(62-63)(62-66)(64-65)(64-68)(65-67)(66-84)(67-69)(68-86)(69-86)(70-78)(70-87)(71-79)(71-87)(72-73)(72-74)(73-76)(74-77)(75-82)(75-85)(76-77)(78-80)(78-83)(79-81)(79-83)(82-88)(83-88)(84-92)(85-92)(86-92)(87-93)(88-94)(89-93)(90-93)(91-93)(92-94)(93-94)
Measurements (3)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| HeLa | 10 | — | 10.1021/acs.inorgchem.2c03279 | 2022 |
| A549 | 21 | — | 10.1021/acs.inorgchem.2c03279 | 2022 |
| BEAS-2B | 35 | — | 10.1021/acs.inorgchem.2c03279 | 2022 |
🧬 Cell Death Types (1)
Apoptosis
high
«The flow cytometry studies indicated that the representative complex Ir1 could induce early-stage apoptosis in A549 cells.»