Info
| ID | 6678 |
| Metal | Os |
| Oxidation state | 2 |
| Charge | 1 |
| Donor atoms | {"O": 1, "N": 3} |
| Abbreviation | 1-VP |
| SMILES | CCCC(CCC)C(=O)[O-].Cc1ccc(C(C)C)cc1.c1ccc(Nc2ccccn2)nc1 |
TUCAN
C28H38N3O2Os/(1-46)(2-47)(3-62)(4-63)(5-61)(6-39)(7-48)(8-39)(9-39)(10-50)(11-40)(12-55)(13-54)(14-54)(15-57)(16-42)(17-42)(18-42)(19-55)(20-60)(21-40)(22-45)(23-52)(24-44)(25-40)(26-51)(27-49)(28-53)(29-43)(30-56)(31-43)(32-41)(33-43)(34-56)(35-57)(36-41)(37-41)(38-67)(39-61)(40-61)(41-59)(42-54)(43-57)(44-45)(44-49)(45-64)(46-47)(46-58)(47-59)(48-50)(48-59)(49-62)(50-58)(51-52)(51-53)(52-65)(53-63)(54-55)(55-60)(56-57)(56-60)(58-61)(60-66)(62-68)(63-69)(64-67)(64-68)(65-67)(65-69)(66-70)(66-71)(68-72)(69-72)
Measurements (4)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A2780 | 21 | — | 10.1039/c8dt00193f | 2018 |
| MCF-7 | — | — | 10.1039/c8dt00193f | 2018 |
| PANC-1 | — | — | 10.1039/c8dt00193f | 2018 |
| HT-29 | — | — | 10.1039/c8dt00193f | 2018 |
🧬 Cell Death Types (1)
Apoptosis
high
«The complexes 1-VP and 1-Cl induced apoptosis of A2780 cells.»