Info
| ID | 6676 |
| Metal | Os |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"N": 1, "O": 2} |
| Abbreviation | 8 |
| SMILES | Cc1ccc(C(C)C)cc1.O=C(CCc1cccnc1)OCCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F.O=C([O-])C(=O)[O-] |
TUCAN
C30H26F17NO6Os/(1-27)(2-27)(3-28)(4-27)(5-36)(6-37)(7-36)(8-31)(9-37)(10-43)(11-30)(12-45)(13-44)(14-38)(15-45)(16-38)(17-28)(18-28)(19-29)(20-42)(21-32)(22-33)(23-34)(24-35)(25-29)(26-29)(27-40)(28-42)(29-42)(30-31)(30-43)(31-39)(32-33)(32-40)(33-41)(34-35)(34-41)(35-40)(36-37)(36-48)(37-39)(38-45)(38-51)(39-44)(41-42)(43-57)(44-57)(45-63)(46-47)(46-58)(46-59)(47-60)(47-61)(48-62)(48-63)(49-50)(49-51)(49-66)(49-69)(50-55)(50-71)(50-79)(51-64)(51-65)(52-53)(52-55)(52-73)(52-74)(53-54)(53-75)(53-76)(54-56)(54-70)(54-80)(55-68)(55-72)(56-67)(56-77)(56-78)(57-81)(63-81)
Measurements (3)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A2780 | 56 | — | 10.1002/cmdc.201500221 | 2015 |
| HEK293 | — | — | 10.1002/cmdc.201500221 | 2015 |
| ECRF24 | — | — | 10.1002/cmdc.201500221 | 2015 |
🧬 Cell Death Types (1)
Apoptosis
high
«Induction of apoptosis was most pronounced for 4 (58.3%) and 7 (52.4%), administrated at a dose of 50 mm. ... This revealed that a significant sub-population of the cells undergoes apoptosis (Table3).»