Info
| ID | 6675 |
| Metal | Os |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"N": 1} |
| Abbreviation | 7 |
| SMILES | Cc1ccc(C(C)C)cc1.O=C(CCc1cccnc1)OCCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F.[Cl-].[Cl-] |
TUCAN
C30Cl2F21NO2Os/(1-14)(2-13)(3-13)(4-7)(4-15)(5-6)(5-16)(6-20)(7-14)(8-9)(8-14)(9-15)(10-11)(10-16)(11-17)(12-19)(12-25)(13-15)(16-18)(17-31)(18-31)(19-33)(20-32)(20-33)(21-22)(21-28)(21-34)(21-35)(22-23)(22-36)(22-37)(23-24)(23-38)(23-39)(24-26)(24-40)(24-41)(25-28)(25-42)(25-45)(26-27)(26-43)(26-44)(27-29)(27-46)(27-47)(28-48)(28-51)(29-30)(29-49)(29-50)(30-52)(30-53)(30-54)
Measurements (3)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A2780 | 56 | — | 10.1002/cmdc.201500221 | 2015 |
| HEK293 | — | — | 10.1002/cmdc.201500221 | 2015 |
| ECRF24 | — | — | 10.1002/cmdc.201500221 | 2015 |
🧬 Cell Death Types (1)
Apoptosis
high
«Induction of apoptosis was most pronounced for 4 (58.3%) and 7 (52.4%), administrated at a dose of 50 mm. ... This revealed that a significant sub-population of the cells undergoes apoptosis (Table3).»