Info
| ID | 6672 |
| Metal | Os |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"N": 1} |
| Abbreviation | 4 |
| SMILES | CCCCCCCCCCCCCCCCCCOC(=O)CCc1cccnc1.Cc1ccc(C(C)C)cc1.[Cl-].[Cl-] |
TUCAN
C36Cl2NO2Os/(1-30)(2-30)(3-27)(4-32)(5-6)(5-26)(6-7)(7-8)(8-9)(9-10)(10-11)(11-12)(12-13)(13-14)(14-15)(15-16)(16-17)(17-18)(18-35)(19-22)(19-33)(20-23)(20-29)(21-25)(21-31)(22-31)(23-32)(24-28)(24-29)(25-36)(26-27)(28-32)(29-30)(31-34)(33-37)(34-37)(35-39)(36-38)(36-39)
Measurements (3)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A2780 | 59 | — | 10.1002/cmdc.201500221 | 2015 |
| HEK293 | — | — | 10.1002/cmdc.201500221 | 2015 |
| ECRF24 | — | — | 10.1002/cmdc.201500221 | 2015 |
🧬 Cell Death Types (1)
Apoptosis
high
«Induction of apoptosis was most pronounced for 4 (58.3%) and 7 (52.4%), administrated at a dose of 50 mm. ... This revealed that a significant sub-population of the cells undergoes apoptosis (Table3).»