Info
| ID | 6671 |
| Metal | Os |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"N": 1} |
| Abbreviation | 3 |
| SMILES | CCCCCCCCCCCCOC(=O)CCc1cccnc1.Cc1ccc(C(C)C)cc1.[Cl-].[Cl-] |
TUCAN
C30Cl2NO2Os/(1-24)(2-24)(3-21)(4-26)(5-6)(5-20)(6-7)(7-8)(8-9)(9-10)(10-11)(11-12)(12-29)(13-16)(13-27)(14-17)(14-23)(15-19)(15-25)(16-25)(17-26)(18-22)(18-23)(19-30)(20-21)(22-26)(23-24)(25-28)(27-31)(28-31)(29-33)(30-32)(30-33)
Measurements (3)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A2780 | — | — | 10.1002/cmdc.201500221 | 2015 |
| HEK293 | — | — | 10.1002/cmdc.201500221 | 2015 |
| ECRF24 | — | — | 10.1002/cmdc.201500221 | 2015 |
🧬 Cell Death Types (1)
Apoptosis
high
«Induction of apoptosis was most pronounced for 4 (58.3%) and 7 (52.4%), administrated at a dose of 50 mm. ... This revealed that a significant sub-population of the cells undergoes apoptosis (Table3).»