Info
| ID | 6670 |
| Metal | Os |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"N": 1} |
| Abbreviation | 2 |
| SMILES | CCCCCCCCCCOC(=O)CCc1cccnc1.Cc1ccc(C(C)C)cc1.[Cl-].[Cl-] |
TUCAN
C28Cl2NO2Os/(1-22)(2-22)(3-19)(4-24)(5-6)(5-18)(6-7)(7-8)(8-9)(9-10)(10-27)(11-14)(11-25)(12-15)(12-21)(13-17)(13-23)(14-23)(15-24)(16-20)(16-21)(17-28)(18-19)(20-24)(21-22)(23-26)(25-29)(26-29)(27-31)(28-30)(28-31)
Measurements (3)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| HEK293 | 65 | — | 10.1002/cmdc.201500221 | 2015 |
| A2780 | — | — | 10.1002/cmdc.201500221 | 2015 |
| ECRF24 | — | — | 10.1002/cmdc.201500221 | 2015 |
🧬 Cell Death Types (1)
Apoptosis
high
«Induction of apoptosis was most pronounced for 4 (58.3%) and 7 (52.4%), administrated at a dose of 50 mm. ... This revealed that a significant sub-population of the cells undergoes apoptosis (Table3).»