Info
| ID | 667 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 2 |
| Donor atoms | {"N": 6} |
| Abbreviation | Ru5 |
| SMILES | CN(C)c1ccc(-n2cc(-c3nc4ccccc4s3)nn2)cc1.c1cnc2c(c1)ccc1cccnc12.c1cnc2c(c1)ccc1cccnc12 |
TUCAN
C41H31N9RuS/(1-36)(2-42)(3-33)(4-35)(5-62)(6-47)(7-58)(8-32)(9-34)(10-56)(11-56)(12-56)(13-57)(14-43)(15-44)(16-38)(17-40)(18-59)(19-46)(20-48)(21-37)(22-60)(23-50)(24-45)(25-39)(26-41)(27-49)(28-51)(29-61)(30-57)(31-57)(32-33)(32-58)(33-52)(34-35)(34-59)(35-53)(36-42)(36-52)(37-38)(37-69)(38-70)(39-40)(39-41)(40-71)(41-47)(42-53)(43-46)(43-54)(44-45)(44-54)(45-60)(46-55)(47-66)(48-49)(48-70)(49-69)(50-51)(50-55)(51-61)(52-63)(53-64)(54-67)(55-68)(56-73)(57-73)(58-76)(59-77)(60-78)(61-79)(62-65)(62-74)(63-64)(63-76)(64-77)(65-72)(65-81)(66-71)(66-80)(67-68)(67-78)(68-79)(69-73)(70-74)(71-82)(72-80)(72-82)(74-75)(75-81)(76-83)(77-83)(78-83)(79-83)(80-83)(81-83)
Measurements (6)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A2780 | — | — | 10.1021/acs.inorgchem.3c04432 | 2024 |
| HeLa | — | — | 10.1021/acs.inorgchem.3c04432 | 2024 |
| A375 | — | — | 10.1021/acs.inorgchem.3c04432 | 2024 |
| CHO | — | — | 10.1021/acs.inorgchem.3c04432 | 2024 |
| HeLa | — | 42 | 10.1021/acs.inorgchem.3c04432 | 2024 |
| A375 | — | 27 | 10.1021/acs.inorgchem.3c04432 | 2024 |
🧬 Cell Death Types (1)
Apoptosis
medium
«The orange triangles indicate the cellular membrane irregularities or blebs associated with apoptosis.»