Info
| ID | 6669 |
| Metal | Os |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"N": 1} |
| Abbreviation | 1 |
| SMILES | CCCCCCCCOC(=O)CCc1cccnc1.Cc1ccc(C(C)C)cc1.[Cl-].[Cl-] |
TUCAN
C26Cl2NO2Os/(1-20)(2-20)(3-17)(4-22)(5-6)(5-16)(6-7)(7-8)(8-25)(9-12)(9-23)(10-13)(10-19)(11-15)(11-21)(12-21)(13-22)(14-18)(14-19)(15-26)(16-17)(18-22)(19-20)(21-24)(23-27)(24-27)(25-29)(26-28)(26-29)
Measurements (3)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A2780 | — | — | 10.1002/cmdc.201500221 | 2015 |
| HEK293 | — | — | 10.1002/cmdc.201500221 | 2015 |
| ECRF24 | — | — | 10.1002/cmdc.201500221 | 2015 |
🧬 Cell Death Types (1)
Apoptosis
high
«Induction of apoptosis was most pronounced for 4 (58.3%) and 7 (52.4%), administrated at a dose of 50 mm. ... This revealed that a significant sub-population of the cells undergoes apoptosis (Table3).»