Info
| ID | 666 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 2 |
| Donor atoms | {"O": 1, "N": 5} |
| Abbreviation | Ru4 |
| SMILES | O=[N+]([O-])c1ccc(-n2cc(-c3nc4ccccc4s3)nn2)cc1.c1cnc2c(c1)ccc1cccnc12.c1cnc2c(c1)ccc1cccnc12 |
TUCAN
C39H25N9O2RuS/(1-26)(2-30)(3-29)(4-31)(5-54)(6-40)(7-50)(8-32)(9-51)(10-33)(11-38)(12-41)(13-36)(14-52)(15-27)(16-53)(17-45)(18-42)(19-39)(20-28)(21-43)(22-34)(23-35)(24-44)(25-37)(26-30)(26-50)(27-38)(27-51)(28-39)(28-52)(29-31)(29-46)(30-46)(31-47)(32-37)(32-48)(33-43)(33-47)(34-35)(34-36)(35-40)(36-63)(37-49)(38-48)(39-49)(40-56)(41-42)(41-62)(42-61)(43-53)(44-45)(44-61)(45-62)(46-57)(47-58)(48-59)(49-60)(50-68)(51-69)(52-70)(53-71)(54-55)(54-65)(55-64)(55-73)(56-63)(56-72)(57-58)(57-68)(58-71)(59-60)(59-69)(60-70)(61-67)(62-65)(63-76)(64-72)(64-76)(65-66)(66-73)(67-74)(67-75)(68-77)(69-77)(70-77)(71-77)(72-77)(73-77)
Measurements (6)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A2780 | — | — | 10.1021/acs.inorgchem.3c04432 | 2024 |
| HeLa | — | — | 10.1021/acs.inorgchem.3c04432 | 2024 |
| A375 | — | — | 10.1021/acs.inorgchem.3c04432 | 2024 |
| CHO | — | — | 10.1021/acs.inorgchem.3c04432 | 2024 |
| HeLa | — | 34 | 10.1021/acs.inorgchem.3c04432 | 2024 |
| A375 | — | 19 | 10.1021/acs.inorgchem.3c04432 | 2024 |
🧬 Cell Death Types (1)
Apoptosis
medium
«The orange triangles indicate the cellular membrane irregularities or blebs associated with apoptosis.»