Info
| ID | 665 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 2 |
| Donor atoms | {"N": 8} |
| Abbreviation | Ru3 |
| SMILES | FC(F)(F)c1ccc(-n2cc(-c3nc4ccccc4s3)nn2)cc1.c1cnc2c(c1)ccc1cccnc12.c1cnc2c(c1)ccc1cccnc12 |
TUCAN
C40H25F3N8RuS/(1-28)(2-27)(3-26)(4-31)(5-30)(6-32)(7-44)(8-54)(9-51)(10-36)(11-52)(12-53)(13-55)(14-34)(15-35)(16-29)(17-33)(18-37)(19-40)(20-43)(21-42)(22-39)(23-41)(24-45)(25-38)(26-30)(26-46)(27-28)(27-46)(28-51)(29-32)(29-52)(30-47)(31-33)(31-47)(32-48)(33-53)(34-35)(34-64)(35-39)(36-38)(36-48)(37-43)(37-55)(38-50)(39-41)(40-44)(40-49)(41-61)(42-45)(42-49)(43-50)(44-62)(45-62)(46-56)(47-58)(48-59)(49-63)(50-60)(51-68)(52-69)(53-70)(54-57)(54-66)(55-71)(56-58)(56-68)(57-65)(57-73)(58-70)(59-60)(59-69)(60-71)(61-64)(61-72)(62-66)(63-74)(63-75)(63-76)(64-77)(65-72)(65-77)(66-67)(67-73)(68-78)(69-78)(70-78)(71-78)(72-78)(73-78)(77-78)
Measurements (6)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A2780 | — | — | 10.1021/acs.inorgchem.3c04432 | 2024 |
| HeLa | — | — | 10.1021/acs.inorgchem.3c04432 | 2024 |
| A375 | — | — | 10.1021/acs.inorgchem.3c04432 | 2024 |
| CHO | — | — | 10.1021/acs.inorgchem.3c04432 | 2024 |
| HeLa | — | 74 | 10.1021/acs.inorgchem.3c04432 | 2024 |
| A375 | — | 74 | 10.1021/acs.inorgchem.3c04432 | 2024 |
🧬 Cell Death Types (1)
Apoptosis
medium
«The orange triangles indicate the cellular membrane irregularities or blebs associated with apoptosis.»