Info
| ID | 664 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 2 |
| Donor atoms | {"N": 8} |
| Abbreviation | Ru2 |
| SMILES | Fc1ccc(-n2cc(-c3nc4ccccc4s3)nn2)cc1.c1cnc2c(c1)ccc1cccnc12.c1cnc2c(c1)ccc1cccnc12 |
TUCAN
C39H25FN8RuS/(1-27)(2-26)(3-28)(4-40)(5-39)(6-29)(7-50)(8-30)(9-34)(10-36)(11-31)(12-41)(13-38)(14-43)(15-54)(16-51)(17-52)(18-42)(19-32)(20-33)(21-53)(22-35)(23-37)(24-44)(25-45)(26-27)(26-46)(27-50)(28-34)(28-46)(29-30)(29-51)(30-47)(31-32)(31-62)(32-58)(33-39)(33-63)(34-47)(35-38)(35-52)(36-41)(36-48)(37-42)(37-53)(38-48)(39-40)(40-43)(41-49)(42-49)(43-61)(44-45)(44-58)(45-62)(46-55)(47-56)(48-57)(49-59)(50-67)(51-68)(52-69)(53-71)(54-60)(54-65)(55-56)(55-67)(56-68)(57-59)(57-69)(58-65)(59-71)(60-64)(60-72)(61-63)(61-70)(62-73)(63-74)(64-70)(64-74)(65-66)(66-72)(67-75)(68-75)(69-75)(70-75)(71-75)(72-75)(74-75)
Measurements (6)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A2780 | — | — | 10.1021/acs.inorgchem.3c04432 | 2024 |
| HeLa | — | — | 10.1021/acs.inorgchem.3c04432 | 2024 |
| A375 | — | — | 10.1021/acs.inorgchem.3c04432 | 2024 |
| CHO | — | — | 10.1021/acs.inorgchem.3c04432 | 2024 |
| HeLa | — | 58 | 10.1021/acs.inorgchem.3c04432 | 2024 |
| A375 | — | 17 | 10.1021/acs.inorgchem.3c04432 | 2024 |
🧬 Cell Death Types (1)
Apoptosis
medium
«The orange triangles indicate the cellular membrane irregularities or blebs associated with apoptosis.»