Info
| ID | 663 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 2 |
| Donor atoms | {"N": 8} |
| Abbreviation | Ru1 |
| SMILES | Cc1ccc(-n2cc(-c3nc4ccccc4s3)nn2)cc1.c1cnc2c(c1)ccc1cccnc12.c1cnc2c(c1)ccc1cccnc12 |
TUCAN
C40H28N8RuS/(1-48)(2-31)(3-32)(4-55)(5-42)(6-30)(7-40)(8-41)(9-57)(10-58)(11-38)(12-45)(13-34)(14-29)(15-29)(16-29)(17-36)(18-46)(19-44)(20-37)(21-49)(22-56)(23-47)(24-39)(25-43)(26-59)(27-35)(28-33)(29-51)(30-31)(30-55)(31-50)(32-34)(32-51)(33-35)(33-51)(34-62)(35-62)(36-43)(36-50)(37-39)(37-52)(38-42)(38-57)(39-53)(40-41)(40-48)(41-67)(42-52)(43-54)(44-45)(44-53)(45-58)(46-47)(46-59)(47-54)(48-49)(49-65)(50-60)(52-61)(53-63)(54-64)(55-71)(56-66)(56-69)(57-72)(58-73)(59-74)(60-64)(60-71)(61-63)(61-72)(62-69)(63-73)(64-74)(65-67)(65-75)(66-68)(66-76)(67-77)(68-75)(68-77)(69-70)(70-76)(71-78)(72-78)(73-78)(74-78)(75-78)(76-78)(77-78)
Measurements (6)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A2780 | — | — | 10.1021/acs.inorgchem.3c04432 | 2024 |
| HeLa | — | — | 10.1021/acs.inorgchem.3c04432 | 2024 |
| A375 | — | — | 10.1021/acs.inorgchem.3c04432 | 2024 |
| CHO | — | — | 10.1021/acs.inorgchem.3c04432 | 2024 |
| HeLa | — | 48 | 10.1021/acs.inorgchem.3c04432 | 2024 |
| A375 | — | 21 | 10.1021/acs.inorgchem.3c04432 | 2024 |
🧬 Cell Death Types (1)
Apoptosis
medium
«The orange triangles indicate the cellular membrane irregularities or blebs associated with apoptosis.»