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Complex #6612 — Os(2) [12]

2D Structure

Structure
⬇ MOL V3000

Info

ID6612
MetalOs
Oxidation state2
Charge1
Donor atoms{"N": 4}
Abbreviation12
SMILESCN(C)c1ccc(/N=N/c2ccccn2)cc1.Cc1ccc(C(C)C)cc1.[I-].c1ccc(-c2ccccc2)cc1

TUCAN

C35H38N4Os/(1-43)(2-42)(3-49)(4-45)(5-44)(6-51)(7-52)(8-50)(9-40)(10-58)(11-59)(12-62)(13-70)(14-48)(15-55)(16-61)(17-60)(18-40)(19-47)(20-40)(21-68)(22-56)(23-57)(24-68)(25-39)(26-67)(27-46)(28-41)(29-53)(30-39)(31-39)(32-41)(33-41)(34-54)(35-68)(36-69)(37-69)(38-69)(39-66)(40-67)(41-67)(42-43)(42-63)(43-49)(44-45)(44-49)(45-63)(46-47)(46-65)(47-66)(48-56)(48-71)(50-52)(50-59)(51-52)(51-64)(53-54)(53-66)(54-65)(55-57)(55-71)(56-72)(57-72)(58-59)(58-64)(60-62)(60-73)(61-62)(61-70)(63-64)(65-67)(68-75)(69-75)(70-74)(71-77)(72-75)(73-74)(73-76)(76-77)(76-78)(77-78)

Measurements (7)

Cell lineIC₅₀ dark (µM)IC₅₀ light (µM)DOIYear
A2780cisR0.11— 10.1021/acs.jmedchem.8b00958 2018
A27800.14— 10.1021/acs.jmedchem.8b00958 2018
A5490.27— 10.1021/acs.jmedchem.8b00958 2018
HCT-116Ox0.33— 10.1021/acs.jmedchem.8b00958 2018
HOF0.35— 10.1021/acs.jmedchem.8b00958 2018
MRC-50.42— 10.1021/acs.jmedchem.8b00958 2018
HCT-1160.82— 10.1021/acs.jmedchem.8b00958 2018