Info
| ID | 6603 |
| Metal | Os |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"N": 2, "O": 1} |
| Abbreviation | 3 |
| SMILES | Cc1ccc(C(C)C)cc1.[NH-][C@H](c1ccccc1)[C@H]([N-]S(=O)(=O)c1ccc([N+](=O)[O-])cc1)c1ccccc1 |
TUCAN
C30H31N3O4OsS/(1-60)(2-52)(3-33)(4-33)(5-33)(6-57)(7-41)(8-35)(9-37)(10-59)(11-40)(12-42)(13-44)(14-43)(15-48)(16-49)(17-47)(18-45)(19-46)(20-50)(21-34)(22-32)(23-32)(24-34)(25-36)(26-38)(27-39)(28-32)(29-51)(30-34)(31-63)(32-53)(33-57)(34-57)(35-49)(35-56)(36-38)(36-53)(37-50)(37-56)(38-54)(39-51)(39-54)(40-41)(40-61)(41-58)(42-44)(42-55)(43-44)(43-45)(45-46)(46-55)(47-48)(47-58)(48-61)(49-52)(50-52)(51-53)(54-57)(55-59)(56-60)(58-62)(59-60)(59-64)(60-63)(61-69)(62-65)(62-66)(63-70)(64-69)(64-70)(67-69)(68-69)(69-70)
Measurements (7)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A2780 | 20 | — | 10.1021/acs.jmedchem.8b00958 | 2018 |
| A2780cisR | 21 | — | 10.1021/acs.jmedchem.8b00958 | 2018 |
| MRC-5 | 22 | — | 10.1021/acs.jmedchem.8b00958 | 2018 |
| A549 | 27 | — | 10.1021/acs.jmedchem.8b00958 | 2018 |
| HCT-116Ox | 64 | — | 10.1021/acs.jmedchem.8b00958 | 2018 |
| HCT-116 | 67 | — | 10.1021/acs.jmedchem.8b00958 | 2018 |
| HOF | — | — | 10.1021/acs.jmedchem.8b00958 | 2018 |