Info
| ID | 6526 |
| Metal | Os |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"N": 1, "O": 1} |
| Abbreviation | 4 |
| SMILES | C1=CCC2=C(C1)Cc1ccccc1C2.Cc1ccnc(C(=O)[O-])c1.[Cl-] |
TUCAN
C21ClNO2Os/(1-15)(2-5)(2-14)(3-14)(3-17)(4-15)(4-19)(5-7)(6-7)(6-16)(8-10)(8-11)(9-16)(9-18)(10-17)(11-12)(12-18)(13-15)(13-20)(14-16)(17-18)(19-22)(20-21)(20-22)(21-23)(21-24)
Measurements (1)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A2780 | 4.5 | — | 10.1021/jm901556u | 2009 |
🧬 Cell Death Types (1)
Apoptosis
medium
«We can therefore conclude that osmium complex 3 and probably the other structurally similar osmium complexes induce cell death via apoptotic pathways rather than necrosis.»